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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Tricin, Docetaxel
Phytochemical Name Tricin (PubChem CID: 5281702 )
Anticancer drug Name Docetaxel (PubChem CID: 148124 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Reversing Drug Resistance
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Combination Pair ID: 477
Pair Name Tricin, Docetaxel
Disease Info [ICD-11: 2C82] Prostate cancer Investigative
Biological Phenomena Inhibition-->Cell proliferation
Gene Regulation Down-regulation Expression MiR-21 KEGG ID N.A.
In Vitro Model PC-3 Prostate carcinoma Homo sapiens (Human) CVCL_0035
Result Tricin can be effective in the reduction of metastasis and drug resistance of Docetaxel.
03. Reference
No. Title Href
1 Tricin isolated from Allium atroviolaceum potentiated the effect of docetaxel on PC3 cell proliferation: role of miR-21. Nat Prod Res. 2019 Jun;33(12):1828-1831. doi: 10.1080/14786419.2018.1437439. Click
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